Herpes zoster ophthalmicus (HZO) is shingles involving the ophthalmic division of the trigeminal nerve — the nerve that supplies sensation to the forehead, scalp, upper eyelid, and parts of the eye itself. It is caused by reactivation of varicella-zoster virus, the same virus that caused your childhood chickenpox. Decades after the original infection, the virus can reactivate from a dormant state in the nerve and travel along its branches, producing the classic painful, blistering rash that respects the midline of the face.
HZO is most common in adults over 50 and in patients with weakened immune systems. About 10 to 20 percent of all shingles episodes involve the eye in some way — and these cases can lead to vision loss if not treated promptly. Treatment combines high-dose oral antivirals to shorten the disease, careful management of any eye involvement, and long-term monitoring for delayed complications including chronic uveitis, glaucoma, and postherpetic neuralgia.
Time matters. If you have a painful rash on one side of your forehead, scalp, or around your eye, see an eye doctor and your primary care provider the same day. Antivirals started within 72 hours of rash onset reduce complications most effectively.
Symptoms
A burning, tingling, or stabbing pain on one side of the forehead, scalp, or upper eyelid — often preceding the rash by days.
Grouped vesicles (blisters) on one side of the forehead, eyelid, or nose — sharply respecting the midline of the face.
Conjunctival redness, light sensitivity, blurred vision, or watering on the affected side.
Rash on the tip or side of the nose — strongly predicts eye involvement and warrants urgent eye examination.
Altered sensation in the forehead and around the eye, sometimes with electric-shock pains.
Many patients feel generally unwell, with mild fever and fatigue, in the days before and after the rash.
Same-day appointments for any patient with a forehead rash and eye involvement — time is the most important factor in HZO outcomes.
Dr. Patel manages both the acute infection and the delayed complications that can affect vision months or years later.
We work directly with your primary care provider on antiviral dosing, pain management, and shingles vaccination for prevention.
Frequently Asked Questions
Herpes zoster ophthalmicus (HZO) is shingles affecting the ophthalmic branch of the trigeminal nerve. It is caused by reactivation of the varicella-zoster virus — the same virus that causes chickenpox. After childhood chickenpox, the virus lies dormant in nerve cells and can reactivate decades later, typically in older adults or those with weakened immunity. About 10 to 20 percent of all shingles cases involve the eye.
The Hutchinson sign is a shingles rash on the tip or side of the nose. It indicates that the nasociliary branch of the trigeminal nerve is involved — the same branch that supplies the eye. Patients with a positive Hutchinson sign have a much higher risk of serious eye involvement and should be evaluated by an eye doctor urgently, even if their eyes look normal at first.
Ideally within 72 hours of the rash appearing. Oral antivirals — acyclovir, valacyclovir, or famciclovir at high doses for 7 to 10 days — significantly reduce the severity of the disease and the risk of complications. Treatment can still help after 72 hours, especially if new lesions are still forming, but the earlier the better.
HZO can cause keratitis (corneal inflammation), uveitis (inflammation inside the eye), elevated eye pressure or glaucoma, scleritis, retinitis, and chronic neurotrophic ulcers due to nerve damage. Many patients also develop postherpetic neuralgia — long-lasting nerve pain in the forehead and eye area that can persist for months or years after the rash heals.
Yes, and it is highly recommended. The Shingrix vaccine is approved for adults 50 and older (and immunocompromised adults 19+), and it is more than 90 percent effective at preventing shingles. Even if you have already had shingles, vaccination is recommended to reduce the risk of recurrence. Talk to your primary care provider about getting vaccinated.